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Effects of cannabis ingestion on endometriosis-associated pelvic pain and related symptoms

According a retrospective electronic record-based study with 252 women by investigators of Western Sydney University and the University of Melbourne, Australia, cannabis may be helpful in the treatment of pain and other symptoms in women suffering from endometriosis. Self-rated cannabis efficacy, defined as a function of initial and final symptom ratings, was investigated across the included symptom clusters of cramps, pelvic pain, gastrointestinal pain, nausea, depression, and low libido.




Participants recorded 16193 sessions using cannabis between April 2017 and February 2020. The most common method of ingestion was inhalation (67.4%), with pain as the most common reported symptom being treated by cannabis (57.3%). Authors concluded that cannabis “appears to be effective for pelvic pain, gastrointestinal issues and mood, with effectiveness differing based on method of ingestion. The greater propensity for use of an inhaled dosage delivery may be due to the rapid onset of pain-relieving effects versus the slower onset of oral products.”


Sinclair J, Collett L, Abbott J, Pate DW, Sarris J, Armour M. Effects of cannabis ingestion on endometriosis-associated pelvic pain and related symptoms. PLoS One. 2021;16(10):e0258940.



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